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KMID : 1143620140180010094
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Korean Journal of Nuclear Medicine Technology
2014 Volume.18 No. 1 p.94 ~ p.97
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Comparative Evaluation for the Effect of SUV's Due to a Residual Radio-activity Location Inside Vascular Insert Devices During PET/CT Scans
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Sim Woo-Yong
Kim Jung-Yul
Cho Seok-Won
Oh Shin-Hyun
Lim Han-Sang
Park Hoon-Hee
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Abstract
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Purpose: Standardized uptake value (SUV) is a simple semi-quantitative method that can measure the ratio of the tissue radioactivity between the tumor and normal. SUV is commonly used in PET/CT, however, SUV is affected by various factor. The purpose of this study was to evaluate the impact of the residual activity on SUV depending on the location of catheter insertion device post injection.
Materials and Methods: NEMA IEC Body Phantom was imaged using a Discovery 600 PET scanner. In 22 mm diameter sphere, the different activity of 18F-FDG (7.4, 14.8, 22.2, 29.6, 37, 55.5 MBq) was filled and background was filled with 18F-FDG (5.7 kBq/mL). We scaned the phantom on the assumption that the radioactivity in sphere was residual activity in insertion device. Simulation of PET was divided into three groups based on the location of sphere in Scan FOV (SFOV); inclusion, 1/2 inclusion and exclusion group.
Results: Among three groups, the group of excluded sphere showed the highest SUV regardless of the amount of 18F-FDG activity. In case of 7.4 MBq, average SUV of inclusion group, 1/2 inclusion and exclusion group was 0.780, 0.840 and 0.896 respectively. However, average SUV of 55.5 MBq showed 0.372, 0.460 and 0.508 with same order. Depend on residual radioactivity in the sphere and position of sphere, the SUV was different minimum of 10.4%, maximum of 62.8%.
Conclusion: This study showed that SUV is underestimated as the residual radio-activity is increased. In addition, SUV was a changed according to the position of residual radio-activity. And among the position, exclusion group showed the difference of SUV was lowest. If we measure the residual radio-activity of inserting devices and radio-activity from extra-vasation in the patients, it seems to be more useful in clinical field.
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KEYWORD
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PET/CT, Injection site, SUV, FOV
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